Gilliland A, Chan JJ, De Wolfe TJ, Yang H, Vallance BA. Pathobionts in Inflammatory Bowel Illness: origins, underlying mechanisms, and implications for Scientific Care. Gastroenterology. 2024;166:44–58.
Lewis JD, Parlett LE, Jonsson Funk ML, Brensinger C, Pate V, Wu Q, Dawwas GK, Weiss A, Fixed BD, McCauley M, et al. Incidence, prevalence, and racial and ethnic distribution of inflammatory bowel illness in the USA. Gastroenterology. 2023;165:1197–e12051192.
Zhang J, Xu M, Zhou W, Li D, Zhang H, Chen Y, Ning L, Zhang Y, Li S, Yu M, et al. Deficiency within the anti-apoptotic protein DJ-1 promotes intestinal epithelial cell apoptosis and aggravates inflammatory bowel illness by way of p53. J Biol Chem. 2020;295:4237–51.
Kotla NG, Isa ILM, Rasala S, Demir S, Singh R, Child BV, Swamy SK, Dockery P, Jala VR, Rochev Y, Pandit A. Modulation of Intestine Barrier capabilities in Ulcerative Colitis by Hyaluronic Acid System. Adv Sci 2021, 9.
Dulai PS, Singh S, Jairath V, Wong E, Narula N. Integrating proof to Information Use of Biologics and Small molecules for Inflammatory Bowel illnesses. Gastroenterology. 2024;166:396–408. e392.
Li J, Niu C, Ai H, Li X, Zhang L, Lang Y, Wang S, Gao F, Mei X, Yu C, et al. TSP50 attenuates DSS-Induced colitis by regulating TGF-beta signaling mediated upkeep of Intestinal Mucosal Barrier Integrity. Adv Sci (Weinh). 2024;11:e2305893.
Takahashi T, Shiga H, Tarasawa Okay, Shimoyama Y, Naito T, Moroi R, Kuroha M, Kakuta Y, Fushimi Okay, Fujimori Okay, et al. Comparative effectiveness of Tacrolimus and Infliximab in hospitalized sufferers with Ulcerative Colitis. Clin Transl Gastroenterol. 2024;15:e00642.
Kreijne JE, Goetgebuer RL, Erler NS, De Boer NK, Siebers AG, Dijkstra G, van Kemenade FA, Hoentjen F, Oldenburg B, van der Meulen AE, et al. Cumulative publicity to immunomodulators will increase danger of cervical neoplasia in girls with inflammatory bowel illness. Aliment Pharmacol Ther. 2023;58:207–17.
Singh S, Allegretti JR, Siddique SM, Terdiman JP. AGA Technical Evaluate on the administration of average to extreme Ulcerative Colitis. Gastroenterology. 2020;158:1465–e14961417.
Zhang Z, Pan Y, Guo Z, Fan X, Pan Q, Gao W, Luo Okay, Pu Y, He B. An olsalazine nanoneedle-embedded inulin hydrogel reshapes intestinal homeostasis in inflammatory bowel illness. Bioactive Mater. 2024;33:71–84.
Zeeshan M, Ain QU, Sunny A, Raza F, Mohsin M, Khan S, Weigmann B, Ali H. QbD-based fabrication of transferrin-anchored nanocarriers for focused drug supply to macrophages and colon cells for mucosal irritation therapeutic. Biomater Sci. 2023;11:1373–97.
Tahara Okay, Samura S, Tsuji Okay, Yamamoto H, Tsukada Y, Bando Y, Tsujimoto H, Morishita R, Kawashima Y. Oral nuclear factor-κB decoy oligonucleotides supply system with chitosan modified poly(d,l-lactide-co-glycolide) nanospheres for inflammatory bowel illness. Biomaterials. 2011;32:870–8.
Ali H, Weigmann B, Neurath MF, Collnot EM, Windbergs M, Lehr CM. Budesonide loaded nanoparticles with pH-sensitive coating for improved mucosal concentrating on in mouse fashions of inflammatory bowel illnesses. J Management Launch. 2014;183:167–77.
Bai X, Feng Z, Peng S, Zhu T, Jiao L, Mao N, Gu P, Liu Z, Yang Y, Wang D. Chitosan-modified Phellinus Igniarius Polysaccharide PLGA nanoparticles ameliorated inflammatory bowel illness. Biomater Adv. 2022;139:213002.
Mao Q, Pan H, Zhang Y, Zhang Y, Zhu Q, Hong Y, Huang Z, Li Y, Feng X, Fang Y, et al. GelNB molecular coating as a biophysical barrier to isolate intestinal irritating metabolites and regulate intestinal microbial homeostasis within the remedy of inflammatory bowel illness. Bioactive Mater. 2023;19:251–67.
Marotti V, Xu Y, Bohns Michalowski C, Zhang W, Domingues I, Ameraoui H, Moreels TG, Baatsen P, Van Hul M, Muccioli GG, et al. A nanoparticle platform for mixed mucosal therapeutic and immunomodulation in inflammatory bowel illness remedy. Bioactive Mater. 2024;32:206–21.
Monajemi H, Meenan J, Lamping R, Obradov DO, Radema SA, Trown PW, Tytgat GN, Van Deventer SJ. Inflammatory bowel illness is related to elevated mucosal ranges of bactericidal/permeability-increasing protein. Gastroenterology. 1996;110:733–9.
Canny G, Levy O, Furuta GT, Narravula-Alipati S, Sisson RB, Serhan CN, Colgan SP. Lipid mediator-induced expression of bactericidal/ permeability-increasing protein (BPI) in human mucosal epithelia. Proc Natl Acad Sci. 2002;99:3902–7.
Li X, Lu C, Yang Y, Yu C, Rao Y. Web site-specific focused drug supply methods for the remedy of inflammatory bowel illness. Biomed Pharmacother. 2020;129:110486.
Zhang S, Langer R, Traverso G. Nanoparticulate Drug Supply methods Focusing on irritation for remedy of inflammatory bowel illness. Nano At the moment. 2017;16:82–96.
Zhang S, Ermann J, Succi MD, Zhou A, Hamilton MJ, Cao B, Korzenik JR, Glickman JN, Vemula PK, Glimcher LH, et al. An inflammation-targeting hydrogel for native drug supply in inflammatory bowel illness. Sci Transl Med. 2015;7:300ra128.
Solar W, Chen Y, Wang L, Wang Z, Liu S, Zhang M, Liu Y, Li Q, Zhang H. Gram-scale preparation of quercetin supramolecular nanoribbons for intestinal inflammatory illnesses by oral administration. Biomaterials. 2023;295:122039.
Nie M, Huang D, Chen G, Zhao Y, Solar L. Bioadhesive Microcarriers Encapsulated with IL-27 excessive expressive MSC Extracellular vesicles for inflammatory bowel Illness Remedy. Adv Sci 2023.
Zhu Y, Wang Y, Xia G, Zhang X, Deng S, Zhao X, Xu Y, Chang G, Tao Y, Li M, et al. Oral supply of Bioactive Glass-Loaded Core-Shell Hydrogel microspheres for Efficient Remedy of Inflammatory Bowel Illness. Adv Sci (Weinh) 2023:e2207418.
Bovone G, Dudaryeva OY, Marco-Dufort B, Tibbitt MW. Engineering Hydrogel Adhesion for Biomedical Functions by way of Chemical Design of the Junction. ACS Biomater Sci Eng. 2021;7:4048–76.
Nam S, Mooney D. Polymeric tissue adhesives. Chem Rev. 2021;121:11336–84.
Lin S, Mukherjee S, Li J, Hou W, Pan C, Liu J. Mucosal immunity-mediated modulation of the intestine microbiome by oral supply of probiotics into Peyer’s patches. Sci Adv 2021, 7.
Li J, Hou W, Lin S, Wang L, Pan C, Wu F, Liu J. Polydopamine nanoparticle-mediated dopaminergic immunoregulation in colitis. Adv Sci (Weinh). 2022;9:e2104006.
Liu H, Cai Z, Wang F, Hong L, Deng L, Zhong J, Wang Z, Cui W. Colon-targeted Adhesive Hydrogel Microsphere for Regulation of Intestine immunity and Flora. Adv Sci (Weinh). 2021;8:e2101619.
He H, Qin Q, Xu F, Chen Y, Rao S, Wang C, Jiang X, Lu X, Xie C. Oral polyphenol-armored nanomedicine for focused modulation of intestine microbiota–mind interactions in colitis. Sci Adv 2023, 9.
Zhao P, Xia X, Xu X, Leung KKC, Rai A, Deng Y, Yang B, Lai H, Peng X, Shi P, et al. Nanoparticle-assembled bioadhesive coacervate coating with extended gastrointestinal retention for inflammatory bowel illness remedy. Nat Commun. 2021;12:7162.
Peng X, Xia X, Xu X, Yang X, Yang B, Zhao P, Yuan W, Chiu PWY, Bian L. Ultrafast self-gelling powder mediates sturdy moist adhesion to advertise therapeutic of gastrointestinal perforations. Sci Adv 2021, 7.
Fu JY, Lai YX, Zheng SS, Wang J, Wang YX, Ren KF, Yu L, Fu GS, Ji J. Mir-22-incorporated polyelectrolyte coating prevents intima hyperplasia after balloon-induced vascular harm. Biomater Sci 2022.
Xue B, Gu J, Li L, Yu W, Yin S, Qin M, Jiang Q, Wang W, Cao Y. Hydrogel tapes for fault-tolerant robust moist adhesion. Nat Commun. 2021;12:7156.
Yao W, Tune Z, Ma X, Huang Y, Zhang X, Li Y, Wei P, Zhang J, Xiong C, Yang S, et al. Uneven adhesive SIS-based wound dressings for therapeutically concentrating on wound restore. J Nanobiotechnol 2024, 22.
Yuk H, Varela CE, Nabzdyk CS, Mao XY, Padera RF, Roche ET, Zhao XH. Dry double-sided tape for adhesion of moist tissues and units. Nature. 2019;575:169–.
Yuk H, Wu J, Sarrafian TL, Mao X, Varela CE, Roche ET, Griffiths LG, Nabzdyk CS, Zhao X. Fast and coagulation-independent haemostatic sealing by a paste impressed by barnacle glue. Nat Biomedical Eng. 2021;5:1131–42.
Mei X, Li J, Wang Z, Zhu D, Huang Okay, Hu S, Popowski KD, Cheng Okay. An inhaled bioadhesive hydrogel to protect non-human primates from SARS-CoV-2 an infection. Nat Mater 2023.
Chen X, Yuk H, Wu J, Nabzdyk CS, Zhao X. Instantaneous robust bioadhesive with triggerable benign detachment. Proc Natl Acad Sci U S A. 2020;117:15497–503.
Wu J, Yuk H, Sarrafian TL, Guo CF, Griffiths LG, Nabzdyk CS, Zhao X. An off-the-shelf bioadhesive patch for sutureless restore of gastrointestinal defects. Sci Transl Med 2022, 14.
Wirtz S, Popp V, Kindermann M, Gerlach Okay, Weigmann B, Fichtner-Feigl S, Neurath MF. Chemically induced mouse fashions of acute and power intestinal irritation. Nat Protoc. 2017;12:1295–309.
El-Hammadi MM, Arias JL. Latest advances within the Floor functionalization of PLGA-Primarily based nanomedicines. Nanomaterials 2022, 12.
Wang XW, Yin YJ, Wang J, Yu HM, Tang Q, Chen ZY, Fu GS, Ren KF, Ji J, Yu L. UV-Triggered hydrogel coating of the double community polyelectrolytes for enhanced endothelialization. Adv Sci (Weinh) 2024:e2401301.
Hu J-Q, Huang W-P, Wang J, Ren Okay-F, Ji J. UV-triggered polymerization of Polyelectrolyte Composite Coating with pore formation and lubricant infusion. Chin J Polym Sci. 2022;41:365–72.
Kotla NG, Singh R, Child BV, Rasala S, Rasool J, Hynes SO, Martin D, Egan LJ, Vemula PK, Jala VR, et al. Irritation-specific focused carriers for native drug supply to inflammatory bowel illness. Biomaterials 2022, 281.
Yoshino T, Nakase H, Honzawa Y, Matsumura Okay, Yamamoto S, Takeda Y, Ueno S, Uza N, Masuda S, Inui Okay, Chiba T. Immunosuppressive results of tacrolimus on macrophages ameliorate experimental colitis. Inflamm Bowel Dis. 2010;16:2022–33.
Ouahed JD, Griffith A, Collen LV, Snapper SB. Breaking down boundaries: epithelial contributors to monogenic IBD pathogenesis. Inflamm Bowel Dis 2024.
Tsukita S, Tanaka H, Tamura A. The claudins: from tight junctions to Organic methods. Developments Biochem Sci. 2019;44:141–52.
Martins C, Sousa F, Araujo F, Sarmento B. Functionalizing PLGA and PLGA derivatives for drug supply and tissue regeneration purposes. Adv Healthc Mater 2018, 7.
Lu X, Miao L, Gao W, Chen Z, McHugh KJ, Solar Y, Tochka Z, Tomasic S, Sadtler Okay, Hyacinthe A, et al. Engineered PLGA microparticles for long-term, pulsatile launch of STING agonist for most cancers immunotherapy. Sci Transl Med 2020, 12.
Zhang J, Solar H, Gao C, Wang Y, Cheng X, Yang Y, Gou Q, Lei L, Chen Y, Wang X, et al. Improvement of a chitosan-modified PLGA nanoparticle vaccine for cover in opposition to Escherichia coli K1 prompted meningitis in mice. J Nanobiotechnol 2021, 19.
Govindarajan Okay, Kar S. Detection of β-amyloid aggregates/plaques in 5xFAD mice by labelled native PLGA nanoparticles: implication within the prognosis of Alzheimer’s illness. J Nanobiotechnol 2023, 21.
Ma J-C, Luo T, Feng B, Huang Z, Zhang Y, Huang H, Yang X, Wen J, Bai X, Cui Z-Okay. Exploring the translational potential of PLGA nanoparticles for intra-articular rapamycin supply in osteoarthritis remedy. J Nanobiotechnol 2023, 21.