Gastric most cancers (GC) is among the main causes of cancer-related mortality worldwide. Regardless of important efforts and up to date advances in GC remedy, therapeutic efficacy stays suboptimal. In recent times, rising nanomaterials have demonstrated appreciable potential for most cancers remedy, primarily on account of their capacity to perform as drug carriers that allow focused and exact supply of therapeutic brokers to tumour tissues. This not solely will increase therapeutic efficacy but additionally reduces unwanted side effects. Herein, we current a complete evaluate of the most important sorts of nanoformulations, together with liposomes, albumin-based nanoparticles (NPs), polymer-based NPs, inorganic NPs, and cell-derived nanomaterials. We additionally study lately reported nanoformulations for numerous GC remedy methods, resembling chemotherapy, radiotherapy, immunotherapy, gene remedy, phototherapy, and mixed remedy. We spotlight the design ideas and ideas underlying these nanoformulations employed in GC remedy. Moreover, we talk about the challenges related to nanoformulation-based therapies for GC in addition to future prospects on this quickly evolving area.