Intermetallic compound (IMC) catalysts have garnered important consideration as a consequence of their distinctive floor and digital properties, which might result in enhanced catalytic efficiency in comparison with conventional monometallic catalysts. Nevertheless, creating IMC supplies as high-performance catalysts has been hindered by the inherent complexity of synthesizing nanoparticles with well-defined bulk and floor compositions. Reaching exact management over the composition of supported bimetallic IMC catalysts, particularly these with excessive floor space and stability, has confirmed difficult. This assessment supplies a complete overview of the current progress in creating supported IMC catalysts. We first look at the varied artificial approaches which have been explored to arrange supported IMC nanoparticles with phase-pure bulk buildings and tailor-made floor compositions. Key components influencing the formation kinetics and compositional management of those supplies are mentioned intimately. Then the methods for manipulating the floor composition of supported IMCs are delved. Functions of high-performance supported IMCs in vital reactions similar to selective hydrogenation, reforming, dehydrogenation, and deoxygenation are comprehensively reviewed, showcasing the distinctive benefits supplied by these supplies. Lastly, the prevailing analysis challenges related to supported IMCs are recognized, together with the necessity for a greater understanding of the composition-property relationships and the event of scalable synthesis strategies. The prospects for the sensible implementation of those versatile catalysts in industrial processes are additionally highlighted, underscoring the significance of continued analysis on this area.