Zhu X, Chan Y, Yung P, Tuan R. Jiang YJFic, biology d: Subchondral Bone Transforming: A Therapeutic Goal for Osteoarthritis. 2020, 8:607764.
Mackie S, Dejaco C, Appenzeller S, Camellino D, Duftner C, Gonzalez-Chiappe S, Mahr A, Mukhtyar C, Reynolds G, de Souza A et al. British Society for Rheumatology guideline on analysis and therapy of big cell arteritis: govt abstract. 2020, 59:487–94.
Belluzzi E, Stocco E, Pozzuoli A, Granzotto M, Porzionato A, Vettor R, De Caro R, Ruggieri P, Ramonda R, Rossato M et al. Contribution of Infrapatellar Fats Pad and Synovial Membrane to Knee Osteoarthritis Ache. 2019, 2019:6390182.
Battistelli M, Favero M, Burini D, Trisolino G, Dallari D, De Franceschi L, Goldring S, Goldring M, Belluzzi E, Filardo G et al. Morphological and ultrastructural evaluation of regular, injured and osteoarthritic human knee menisci. 2019, 63.
Rice S, Tselepi M, Sorial A, Aubourg G, Shepherd C, Almarza D, Skelton A, Pangou I, Deehan D, Reynard L et al. Prioritization of PLEC and GRINA as Osteoarthritis Threat genes by means of the identification and characterization of novel methylation quantitative trait loci. 2019, 71:1285–96.
Hunter DJ, Bierma-Zeinstra S, Osteoarthritis. Lancet. 2019;393:1745–59.
Loeser RF, Goldring SR, Scanzello CR, Goldring MB. Osteoarthritis: a illness of the joint as an organ. Arthritis Rheum. 2012;64:1697–707.
Mahmoudian A, Lohmander LS, Mobasheri A, Englund M, Luyten FP. Early-stage symptomatic osteoarthritis of the knee – time for motion. Nat Rev Rheumatol. 2021;17:621–32.
Lin J, Zhang W, Jones A, Doherty M. Efficacy of topical non-steroidal anti-inflammatory medication within the therapy of osteoarthritis: meta-analysis of randomised managed trials. BMJ. 2004;329:324.
Filardo G, Vannini F, Marcacci M, Andriolo L, Ferruzzi A, Giannini S, Kon E. Matrix-assisted autologous chondrocyte transplantation for cartilage regeneration in osteoarthritic knees. Am J Sports activities Med. 2012;41:95–100.
Dowthwaite G, Bishop J, Redman S, Khan I, Rooney P, Evans D, Haughton L, Bayram Z, Boyer S, Thomson B et al. The floor of articular cartilage incorporates a progenitor cell inhabitants. 2004, 117:889–97.
Xue Okay, Zhang X, Gao Z, Xia W, Qi L, Liu Okay. Cartilage progenitor cells mixed with PHBV in cartilage tissue engineering. J Translational Med 2019, 17.
Jiang Y, Cai Y, Zhang W, Yin Z, Hu C, Tong T, Lu P, Zhang S, Neculai D, Tuan RS, Ouyang HW. Human cartilage-derived progenitor cells from dedicated chondrocytes for environment friendly cartilage restore and regeneration. Stem Cells Transl Med. 2016;5:733–44.
Rikkers M, Korpershoek JV, Levato R, Malda J, Vonk LA. Progenitor cells in wholesome and osteoarthritic human cartilage have in depth tradition growth capability whereas retaining Chondrogenic Properties. Cartilage. 2021;13:S129–42.
Ferguson GB, Van Handel B, Bay M, Fiziev P, Org T, Lee S, Shkhyan R, Banks NW, Scheinberg M, Wu L, et al. Mapping molecular landmarks of human skeletal ontogeny and pluripotent stem cell-derived articular chondrocytes. Nat Commun. 2018;9:3634.
Vinod E, Parameswaran R, Manickam Amirtham S, Livingston A, Ramasamy B, Kachroo U. Comparability of the effectivity of laminin versus fibronectin as a differential adhesion assay for isolation of human articular cartilage derived chondroprogenitors. Join Tissue Res. 2021;62:427–35.
Jiang Z, Yu S, Lin H, Bi R. Expression and performance of cartilage-derived pluripotent cells in joint growth and restore. Stem Cell Res Ther. 2020;11:111.
Vinod E, Parameswaran R, Ramasamy B, Kachroo U. Pondering the potential of Hyaline cartilage-derived chondroprogenitors for tissue regeneration: a scientific evaluate. Cartilage. 2021;13:S34–52.
Wang Okay, Li J, Li Z, Wang B, Qin Y, Zhang N, Zhang H, Su X, Wang Y, Zhu H. Chondrogenic progenitor cells exhibit Superiority over mesenchymal stem cells and chondrocytes in platelet-rich plasma Scaffold-based cartilage regeneration. Am J Sports activities Med. 2019;47:2200–15.
Gu J, Wang B, Wang T, Zhang N, Liu H, Gui J, Lu Y. Results of Cartilage Progenitor cells, bone marrow mesenchymal stem cells and chondrocytes on cartilage restore as seed cells: an in vitro examine. Drug Des Devel Ther. 2022;16:1217–30.
Rodriguez Ruiz A, Dicks A, Tuerlings M, Schepers Okay, van Pel M, Nelissen R, Freund C, Mummery CL, Orlova V, Guilak F, et al. Cartilage from human-induced pluripotent stem cells: comparability with neo-cartilage from chondrocytes and bone marrow mesenchymal stromal cells. Cell Tissue Res. 2021;386:309–20.
Ma Q, Liao J, Cai X. Completely different sources of stem cells and their software in cartilage tissue Engineering. Curr Stem Cell Res Ther. 2018;13:568–75.
Ni Z, Zhou S, Li S, Kuang L, Chen H, Luo X, Ouyang J, He M, Du X, Chen L. Exosomes: roles and therapeutic potential in osteoarthritis. Bone Res. 2020;8:25.
Yin B, Ni J, Witherel CE, Yang M, Burdick JA, Wen C, Wong SHD. Harnessing tissue-derived Extracellular vesicles for Osteoarthritis Theranostics. Theranostics. 2022;12:207–31.
Zhang S, Teo KYW, Chuah SJ, Lai RC, Lim SK, Toh WS. MSC exosomes alleviate temporomandibular joint osteoarthritis by attenuating irritation and restoring matrix homeostasis. Biomaterials. 2019;200:35–47.
Woo CH, Kim HK, Jung GY, Jung YJ, Lee KS, Yun YE, Han J, Lee J, Kim WS, Choi JS, et al. Small extracellular vesicles from human adipose-derived stem cells attenuate cartilage degeneration. J Extracell Vesicles. 2020;9:1735249.
Wang R, Jiang W, Zhang L, Xie S, Zhang S, Yuan S, Jin Y, Zhou G. Intra-articular supply of extracellular vesicles secreted by chondrogenic progenitor cells from MRL/MpJ superhealer mice enhances articular cartilage restore in a mouse harm mannequin. Stem Cell Res Ther. 2020;11:93.
Sarkar A, Liu NQ, Magallanes J, Tassey J, Lee S, Shkhyan R, Lee Y, Lu J, Ouyang Y, Tang H, et al. STAT3 promotes a youthful epigenetic state in articular chondrocytes. Getting old Cell. 2023;22:e13773.
Chen B, Ning Okay, Solar ML, Zhang XA. Regulation and remedy, the position of JAK2/STAT3 signaling pathway in OA: a scientific evaluate. Cell Commun Sign. 2023;21:67.
Han JH, Ju JH, Lee YS, Park JH, Yeo IJ, Park MH, Roh YS, Han SB, Hong JT. Astaxanthin alleviated ethanol-induced liver harm by inhibition of oxidative stress and inflammatory responses through blocking of STAT3 exercise. Sci Rep. 2018;8:14090.
Liang T, Chen T, Qiu J, Gao W, Qiu X, Zhu Y, Wang X, Chen Y, Zhou H, Deng Z, et al. Inhibition of nuclear receptor RORalpha attenuates cartilage injury in osteoarthritis by modulating IL-6/STAT3 pathway. Cell Demise Dis. 2021;12:886.
Latourte A, Cherifi C, Maillet J, Ea H, Bouaziz W, Funck-Brentano T, Cohen-Solal M, Hay E. Richette PJAotrd: systemic inhibition of IL-6/Stat3 signalling protects towards experimental osteoarthritis. 2017, 76:748–55.
Pei W, Huang X, Ni B, Zhang R, Niu G. You HJFip: viaSelective STAT3 inhibitor Alantolactone ameliorates Osteoarthritis regulating Chondrocyte Autophagy and Cartilage Homeostasis. 2021, 12:730312.
Chen B, Ning Okay, Solar M, Zhang, XJCc. CCS s: regulation and remedy, the position of JAK2/STAT3 signaling pathway in OA: a scientific evaluate. 2023, 21:67.
Vinod E, Kachroo U, Amirtham SM, Ramasamy B, Sathishkumar S. Comparative evaluation of recent chondrocytes, cultured chondrocytes and chondroprogenitors derived from human articular cartilage. Acta Histochem. 2020;122:151462.
Kachroo U, Zachariah SM, Thambaiah A, Tabasum A, Livingston A, Rebekah G, Srivastava A, Vinod E. Comparability of human platelet lysate versus fetal bovine serum for growth of human articular cartilage-derived chondroprogenitors. Cartilage. 2021;13:S107–16.
Feng Okay, Xie X, Yuan J, Gong L, Zhu Z, Zhang J, Li H, Yang Y, Wang Y. Reversing the floor cost of MSC-derived small extracellular vesicles by epsilonPL-PEG-DSPE for enhanced osteoarthritis therapy. J Extracell Vesicles. 2021;10:e12160.
Feng Okay, Chen Z, Pengcheng L, Zhang S, Wang XJJ. Quercetin attenuates oxidative stress-induced apoptosis through SIRT1/AMPK-mediated inhibition of ER stress in rat chondrocytes and prevents the development of osteoarthritis in a rat mannequin. 2019, 234:18192–205.
Feng Okay, Ge Y, Chen Z, Li X, Liu Z, Li X, Li H, Tang T, Yang F. Wang XJOm, longevity c: αCurcumin Inhibits the PERK-eIF2-CHOP Pathway by means of Selling SIRT1 Expression in Oxidative Stress-induced Rat Chondrocytes and Ameliorates Osteoarthritis Development in a Rat Mannequin. 2019, 2019:8574386.
Wu J, Kuang L, Chen C, Yang J, Zeng WN, Li T, Chen H, Huang S, Fu Z, Li J, et al. Mir-100-5p-abundant exosomes derived from infrapatellar fats pad MSCs shield articular cartilage and ameliorate gait abnormalities through inhibition of mTOR in osteoarthritis. Biomaterials. 2019;206:87–100.
Balaganur V, Pathak N, Lingaraju M, Extra A, Latief N, Kumari R, Kumar D. Tandan SJTJop, pharmacology: Chondroprotective and anti inflammatory results of S-methylisothiourea, an inducible nitric oxide synthase inhibitor in cartilage and synovial explants mannequin of osteoarthritis. 2014, 66:1021–31.
Xia Y, Hu G, Chen Y, Yuan J, Zhang J, Wang S, Li Q, Wang Y, Deng Z. Embryonic stem cell derived Small Extracellular Vesicles Modulate Regulatory T Cells to guard towards ischemic stroke. ACS Nano. 2021;15:7370–85.
Gong L, Chen B, Zhang J, Solar Y, Yuan J, Niu X, Hu G, Chen Y, Xie Z, Deng Z, et al. Human ESC-sEVs alleviate age-related bone loss by rejuvenating senescent bone marrow-derived mesenchymal stem cells. J Extracell Vesicles. 2020;9:1800971.
Glasson SS, Chambers MG, Van Den Berg WB, Little CB. The OARSI histopathology initiative – suggestions for histological assessments of osteoarthritis within the mouse. Osteoarthritis Cartilage. 2010;18(Suppl 3):S17–23.
Jeon OH, Kim C, Laberge RM, Demaria M, Rathod S, Vasserot AP, Chung JW, Kim DH, Poon Y, David N, et al. Native clearance of senescent cells attenuates the event of post-traumatic osteoarthritis and creates a pro-regenerative atmosphere. Nat Med. 2017;23:775–81.
Yang S, Kim J, Ryu J, Oh H, Chun C, Kim B, Min B. Chun JJNm: Hypoxia-inducible factor-2alpha is a catabolic regulator of osteoarthritic cartilage destruction. 2010, 16:687–93.
Zhu Z, Gao R, Ye T, Feng Okay, Zhang J, Chen Y, Xie Z, Wang Y. The therapeutic impact of iMSC-Derived small Extracellular vesicles on Tendinopathy Associated Ache by means of assuaging irritation: an in vivo and in vitro examine. J Inflamm Res. 2022;15:1421–36.
Wright R. JTJob, quantity jsA: Osteoarthritis Classification Scales: Interobserver Reliability and Arthroscopic Correlation. 2014, 96:1145–1151.
Liu W, Feng M, Xu PJF. Biology d: from regeneration to osteoarthritis within the knee joint: the position shift of cartilage-derived progenitor cells. 2022, 10:1010818.
Alsalameh S, Amin R, Gemba T, Lotz MJA. Rheumatism: identification of mesenchymal progenitor cells in regular and osteoarthritic human articular cartilage. 2004, 50:1522–32.
Latourte A, Kloppenburg M, Richette. Rising pharmaceutical therapies for osteoarthritis. PJNrR. 2020;16:673–88.
Gao J, Xia Z, Mary HB, Joseph J, Luo JN, Joshi N. Overcoming limitations for intra-articular supply of disease-modifying osteoarthritis medication. Traits Pharmacol Sci. 2022;43:171–87.
Vinod E, Vinod Francis D, Manickam Amirtham S, Sathishkumar S, Boopalan P. Allogeneic platelet wealthy plasma serves as a scaffold for articular cartilage derived chondroprogenitors. Tissue Cell. 2019;56:107–13.
Bi R, Yin Q, Mei J, Chen Okay, Luo X, Fan Y, Zhu S. Identification of human temporomandibular joint fibrocartilage stem cells with distinct chondrogenic capability. Osteoarthritis Cartilage. 2020;28:842–52.
Richardson SM, Kalamegam G, Pushparaj PN, Matta C, Memic A, Khademhosseini A, Mobasheri R, Poletti FL, Hoyland JA, Mobasheri A. Mesenchymal stem cells in regenerative drugs: deal with articular cartilage and intervertebral disc regeneration. Strategies. 2016;99:69–80.
Kangari P, Talaei-Khozani T, Razeghian-Jahromi I, Razmkhah M. Mesenchymal stem cells: superb treatments for bone and cartilage defects. Stem Cell Res Ther. 2020;11:492.
Connelly JT, Wilson CG, Levenston ME. Characterization of proteoglycan manufacturing and processing by chondrocytes and BMSCs in tissue engineered constructs. Osteoarthritis Cartilage. 2008;16:1092–100.
Greene MA, Loeser RF. Getting old-related irritation in osteoarthritis. Osteoarthritis Cartilage. 2015;23:1966–71.
Goldring MB, Otero M. Irritation in osteoarthritis. Curr Opin Rheumatol. 2011;23:471–8.
Lieberthal J, Sambamurthy N, Scanzello CR. Irritation in joint harm and post-traumatic osteoarthritis. Osteoarthritis Cartilage. 2015;23:1825–34.
Kawata M, Teramura T, Ordoukhanian P, Head S, Natarajan P, Sundaresan A, Olmer M, Asahara H. Lotz MJAotrd: Krüppel-like factor-4 and Krüppel-like factor-2 are vital regulators of joint tissue cells and shield towards tissue destruction and irritation in osteoarthritis. 2022.
Zhang L, Chen X, Cai P, Solar H, Shen S, Guo B. Jiang QJAm: reprogramming mitochondrial metabolism in synovial macrophages of early osteoarthritis by a camouflaged Meta-defensome. 2022, 34:e2202715.
Quero L, Tiaden A, Hanser E, Roux J, Laski A, Corridor J. Kyburz DJFii: mir-221-3p drives the shift of M2-Macrophages to a pro-inflammatory perform by suppressing JAK3/STAT3 activation. 2019, 10:3087.
Liu W, Lengthy Q, Zhang W, Zeng D, Hu B, Liu S, Chen LJA. miRNA-221-3p derived from M2-polarized tumor-associated macrophage exosomes aggravates the expansion and metastasis of osteosarcoma by means of SOCS3/JAK2/STAT3 axis. 2021, 13:19760–75.